dTaP/IPV (4 in 1) vaccine - 4 in 1 vaccine information for health professionals
Boostrix-IPV is an inactivated injectable vaccine in a pre-filled syringe presentation. Boostrix-IPV contains reduced content of diphtheria, tetanus and pertussis antigens in combination with poliomyelitis antigens.
Boostrix-IPV (‘4-in-1’) can be used in the management of tetanus prone injuries in persons.
Guidance on the treatment of tetanus cases and management of tetanus prone wounds is available at the UK Government website (external site).
Tetanus immunoglobulin should be administered concomitantly in accordance with official recommendations.
Summary of product characteristics
The complete routine immunisation schedule includes information about routine and non-routine vaccination.
Guidance
Vaccination programme recommendations from the Joint Committee on Vaccination and Immunisation (JCVI) and Welsh Government policy can be found at the links below.
Joint Committee on Vaccination and Immunisation on the UK Government website (external site) – read JCVI publications and statements; search e.g. polio.
Welsh Health Circulars and Welsh Government letters
- Urgent polio catch-up programme for children under 5 years old on the Welsh Government website (external site).
- Pertussis vaccination for healthcare workers on the Welsh Government website (external site).
- Change to the pertussis vaccination programme for pregnant women on the Welsh Government website (external site).
- Children who have outstanding routine immunisations: national enhanced service specification on the Welsh Government website (external site).
Clinical resources and information
- Diphtheria: the green book, chapter 15 on the UK Government website (external site).
- Tetanus: the green book, chapter 30 on the UK Government website (external site).
- Pertussis: the green book, chapter 24 on the UK Government website (external site).
- Polio: the green book, chapter 26 on the UK Government website (external site).
- Tetanus: advice for health professionals on the UK Government website (external site).
- Vaccination of individuals with uncertain or incomplete immunisation status by the UKHSA on the UK Government website (external site).
- Polio catch-up in under 5s: Core Script to support conversations with parents/guardians Welsh Government/Public Health Wales October 2022.
Patient group directions (PGDs) and protocols
PGD templates for vaccines can be found on the patient group directions (PGDs) and protocols page (external site).
Further clinical resources and information
Data and surveillance
Vaccination surveillance information can be found on the pages below:
- Immunisation surveillance.
- Diphtheria disease: guidance, data and analysis from UKHSA on the UK Government website (external site).
- Tetanus: guidance, data and analysis from UKHSA on the UK Government website (external site).
- Pertussis: guidance, data and analysis from UKHSA on the UK Government website (external site).
- Polio: guidance, data and analysis from UKHSA on the UK Government website (external site).
Page last reviewed: 4th August 2025