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3rd Generation Cephalosporin resistance in Wales 2008

Details:

Published on: 9th September 2010

  • All Wales/National

All Wales 3GC targeted surveillance study

Carbapenem resistance in Gram-negative bacteria is an increasing problem across Wales and the World, resulting in treatment failures and contributing a significant risk to the patient. Third generation cephalosporin (3GC) resistance in Gram-negative bacteria drives carbapenem use and may contribute to increasing levels of resistance.

It is therefore important to determine the levels of 3GC resistance in Gram-negative bacteria; every 5 years SACU will collect a cross section of 3GC resistant Enterobactericeae strains isolated in Welsh laboratories and investigate the mechanisms of resistance.

In 2008 and 2014 SACU collected approximately 1/6th of all 3GC resistant Enterobacteriaceae across Wales. Details of the 2008 collection can be seen in the report below. We are currently collecting strains isolated during 2020 to 2021. Next collection is likely to be 2025 to 2026.

Table of contents:

2020 surveillance

We would like to continue our surveillance of 3rd generation cephalosporin resistance in Wales by asking all laboratories to submit the following isolates to SACU:
Hospital Location No. Requested Hospital E.coli Hospital Coliform GP E.coli GP Coliform
Bronglais Hospital, Aberystwyth 32 6 4 17 5
Royal Gwent, Newport (incl. Royal Glamorgan) 196 39 62 54 41
UHW, Cardiff 169 48 29 68 24
Singleton, Swansea 226 25 90 27 84
WWGH, Carmarthen 129 26 30 36 37
Ysbyty Glan Clwyd, Rhyl (incl Maelor & Bangor) 259 62 45 102 50
Total 1011 206 260 304 241

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3rd Generation Cephalosporin Resistance in Wales 2008

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